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Issue 29, 2018
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Fe-Catalyzed tandem cyclization for the synthesis of 3-nitrofurans from homopropargylic alcohols and Al(NO3)3·9H2O

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Abstract

Al(NO3)3·9H2O as a nitro source for the synthesis of 3-nitrofurans from homopropargylic alcohols through Fe-catalyzed tandem cyclization is described. In this transformation, the substituted nitrofurans are obtained through nitration and cyclization. The substrate homopropargylic alcohols with different groups participate smoothly in this process and the desired substituted nitrofurans were obtained in moderate yields.

Graphical abstract: Fe-Catalyzed tandem cyclization for the synthesis of 3-nitrofurans from homopropargylic alcohols and Al(NO3)3·9H2O

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Publication details

The article was received on 20 May 2018, accepted on 29 Jun 2018 and first published on 02 Jul 2018


Article type: Communication
DOI: 10.1039/C8OB01184B
Citation: Org. Biomol. Chem., 2018,16, 5232-5235
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    Fe-Catalyzed tandem cyclization for the synthesis of 3-nitrofurans from homopropargylic alcohols and Al(NO3)3·9H2O

    T. Wang, Y. Jiang, Y. Wang and R. Yan, Org. Biomol. Chem., 2018, 16, 5232
    DOI: 10.1039/C8OB01184B

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