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Issue 23, 2018
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FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

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Abstract

An intriguing conversion of arylglyoxal, cyclic dicarbonyl compounds and phenols to diverse furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic protocol, a variety of furan analogues could be easily obtained in moderate to good yields with different substituted patterns by varying the reaction medium. Atom-economical characteristics and mild conditions of this method are in accord with the concept of modern green chemistry.

Graphical abstract: FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

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Publication details

The article was received on 21 Apr 2018, accepted on 16 May 2018 and first published on 18 May 2018


Article type: Paper
DOI: 10.1039/C8OB00942B
Citation: Org. Biomol. Chem., 2018,16, 4279-4287
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    FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

    X. Chang, X. Zhang and Z. Chen, Org. Biomol. Chem., 2018, 16, 4279
    DOI: 10.1039/C8OB00942B

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