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Issue 47, 2018
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An ultrathin iron-porphyrin based nanocapsule with high peroxidase-like activity for highly sensitive glucose detection

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Abstract

For the first time, an ultrathin iron-porphyrin based polymer nanocapsule with multiple peroxidase-like catalytic centers was constructed by covalently assembling iron-porphyrin monomers; this nanocapsule with a single molecule thickness shell acted as a highly efficient artificial enzyme for mimicking peroxidase. On the basis of the peroxidase-like activity of Fe-TPyP based nanocapsules (Fe-TPyP NCs), a highly sensitive colorimetric sensor for glucose determination was fabricated, the limit of detection was found to be as low as 0.098 μM. This study provided a novel strategy for developing artificial enzymes based on covalently assembled nanostructures. Furthermore, the colorimetric sensor for glucose determination showed potential applications in biomedicine and biology.

Graphical abstract: An ultrathin iron-porphyrin based nanocapsule with high peroxidase-like activity for highly sensitive glucose detection

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Publication details

The article was received on 07 Sep 2018, accepted on 05 Nov 2018 and first published on 26 Nov 2018


Article type: Communication
DOI: 10.1039/C8NR07288D
Citation: Nanoscale, 2018,10, 22155-22160
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    An ultrathin iron-porphyrin based nanocapsule with high peroxidase-like activity for highly sensitive glucose detection

    X. Fan, R. Tian, T. Wang, S. Liu, L. Wang, J. Xu, J. Liu, M. Ma and Z. Wu, Nanoscale, 2018, 10, 22155
    DOI: 10.1039/C8NR07288D

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