Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 8, 2018
Previous Article Next Article

Silicon nanohybrid-based SERS chips armed with an internal standard for broad-range, sensitive and reproducible simultaneous quantification of lead(ii) and mercury(ii) in real systems

Author affiliations

Abstract

Lead ions (Pb2+) and mercury ions (Hg2+), the two commonly coexisting heavy metal ions, pose severe risks to environment and human health. To date, no surface-enhanced Raman scattering (SERS) sensor has been reported for the simultaneous quantification of Pb2+ and Hg2+ in real systems. Herein, the first demonstration of SERS chips for simultaneous quantification of Pb2+ and Hg2+ in real systems is presented based on the combination of reproducible silicon nanohybrid substrates and a corrective internal standard (IS) sensing strategy. This chip was made of a silver nanoparticle-decorated silicon wafer via modification of the IS, i.e. 4-aminothiophenol, molecules. The as-prepared chip was further functionalized with Pb2+- and Hg2+- specific DNA strands capable of simultaneously detecting Pb2+ and Hg2+. Quantitatively, upon correction by the IS Raman signals, the broad dynamic ranges from 100 pM to 10 μM for Pb2+ and from 1 nM to 10 μM for Hg2+ were achieved, with the detection limit down to 19.8 ppt for Pb2+ and 168 ppt for Hg2+. For real applications, we further demonstrated that Pb2+ and Hg2+ spiked into industrial wastewater could be readily distinguished via the presented chip, and the relative standard deviation (RSD) value was less than ∼15%. More significantly, the resulting SERS chip can be well coupled with a hand-held Raman instrument and can then be used for the qualitative analysis of both Pb2+ and Hg2+ in real systems in a portable manner. Our results suggest that this high-quality SERS chip is a powerful tool for on-site detection of various heavy metal ions in real samples in the field of food safety and environment protection.

Graphical abstract: Silicon nanohybrid-based SERS chips armed with an internal standard for broad-range, sensitive and reproducible simultaneous quantification of lead(ii) and mercury(ii) in real systems

Back to tab navigation

Supplementary files

Article information


Submitted
25 Oct 2017
Accepted
24 Jan 2018
First published
24 Jan 2018

Nanoscale, 2018,10, 4010-4018
Article type
Paper

Silicon nanohybrid-based SERS chips armed with an internal standard for broad-range, sensitive and reproducible simultaneous quantification of lead(II) and mercury(II) in real systems

Y. Shi, N. Chen, Y. Su, H. Wang and Y. He, Nanoscale, 2018, 10, 4010
DOI: 10.1039/C7NR07935D

Social activity

Search articles by author

Spotlight

Advertisements