Jump to main content
Jump to site search

L-cysteine-Mediated, Iodide-Catalyzed Reaction for detection of I-


In this paper, a highly selective and eco-friendly fluorescence sensor consisting of upconversion (UCNPs) and gold nanoparticles (AuNPs) has been developed for the detection of I-. The negatively charged AuNPs could be electrostatically adsorbed on the positively charged UCNPs, leading to the fluorescence quenching of UCNPs. In the presence of L-cysteine, AuNPs released from the surface of UCNPs and aggregated due to the Au-S interaction between AuNPs and L-cysteine, which resulted in the fluorescence recovery of UCNPs. Upon addition of I-, the fluorescence of UCNPs was quenched gradually in that I- can catalyze the oxidation of L-cysteine, preventing the aggregation of AuNPs and forming the fluorescence energy resonance transfer system. The I--catalyzed oxidation reaction provides a method of a L-cysteine-triggered sensor to detect I-, using L-cysteine to modulate the fluorescence signal, which manifests eco-friendly. Based on the above special detection strategies, this sensor has excellent selectivity for I- even in a complex matrix such as urine, which is much better than most assays for I-. Under the optimal conditions, the sensor allows the quantitative analysis of I- with a detection limit of 55 nM. The high selectivity, sensitivity and environmental friendliness of the sensor proves that it has the potential for the detection of I- in actual samples. Most importantly, the excellent results of the sensor for detection of I- in urine prove that the probe can be used as an ideal tool in clinic diagnoses.

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 Sep 2018, accepted on 25 Nov 2018 and first published on 04 Dec 2018

Article type: Paper
DOI: 10.1039/C8NJ04944K
Citation: New J. Chem., 2018, Accepted Manuscript
  •   Request permissions

    L-cysteine-Mediated, Iodide-Catalyzed Reaction for detection of I-

    K. He, H. Chen, C. Wu, M. Liu and Y. Zhang, New J. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8NJ04944K

Search articles by author