Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 22, 2018
Previous Article Next Article

A Rh(III)-catalyzed cascade C–H functionalization/cyclization reaction of salicylaldehydes with diazomalonates for the synthesis of 4-hydroxycoumarin derivatives

Author affiliations

Abstract

A cascade C–H functionalization/cyclization reaction of salicylaldehydes with α-diazomalonates has been developed for the synthesis of 4-hydroxycoumarin derivatives under the catalysis of rhodium(III) and in the presence of acetic acid. A plausible mechanism involving aldehydic C(sp2)–H activation by rhodium(III) and rhodium(III) catalyzed carbene insertion is also proposed.

Graphical abstract: A Rh(iii)-catalyzed cascade C–H functionalization/cyclization reaction of salicylaldehydes with diazomalonates for the synthesis of 4-hydroxycoumarin derivatives

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Sep 2018, accepted on 08 Oct 2018 and first published on 23 Oct 2018


Article type: Paper
DOI: 10.1039/C8NJ04576C
New J. Chem., 2018,42, 18358-18362

  •   Request permissions

    A Rh(III)-catalyzed cascade C–H functionalization/cyclization reaction of salicylaldehydes with diazomalonates for the synthesis of 4-hydroxycoumarin derivatives

    G. Xu and Z. Huang, New J. Chem., 2018, 42, 18358
    DOI: 10.1039/C8NJ04576C

Search articles by author

Spotlight

Advertisements