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Issue 12, 2018
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A physico-chemical investigation of fluorine-enriched quinolines

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Abstract

Quinoline derivatives bearing fluoroalkyl groups at both 2 and 4 positions are scarcely described in the literature. Nevertheless, the addition of fluorine onto the quinoline core might bring about new interesting physico-chemical properties. To confirm this hypothesis a homogenous series of 2,4-bis(fluoroalkyl)-substituted quinolines was synthesized under mild reaction conditions and their physico-chemical properties were thoroughly investigated by various techniques to illustrate their potential usefulness as new building blocks for applications ranging from organic chemistry to materials science.

Graphical abstract: A physico-chemical investigation of fluorine-enriched quinolines

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Article information


Submitted
23 Feb 2018
Accepted
21 Apr 2018
First published
23 Apr 2018

New J. Chem., 2018,42, 10036-10047
Article type
Paper

A physico-chemical investigation of fluorine-enriched quinolines

F. Aribi, A. Panossian, D. Jacquemin, J. Vors, S. Pazenok, F. R. Leroux and M. Elhabiri, New J. Chem., 2018, 42, 10036
DOI: 10.1039/C8NJ00916C

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