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Issue 6, 2018
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Engineering hyperthermostable rcSso7d as reporter molecule for in vitro diagnostic tests

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Abstract

The hyperthermostable binding scaffold, rcSso7d, has recently been studied for use in in vitro diagnostic tests but has not yet been demonstrated as a soluble reporter protein. Here, we investigated several rcSso7d protein constructs and biotin conjugation methods to link a detectable signal to the presence of a target biomarker.

Graphical abstract: Engineering hyperthermostable rcSso7d as reporter molecule for in vitro diagnostic tests

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Supplementary files

Article information


Submitted
31 Jul 2018
Accepted
15 Oct 2018
First published
15 Oct 2018

This article is Open Access

Mol. Syst. Des. Eng., 2018,3, 877-882
Article type
Communication

Engineering hyperthermostable rcSso7d as reporter molecule for in vitro diagnostic tests

K. Sung, E. A. Miller and H. D. Sikes, Mol. Syst. Des. Eng., 2018, 3, 877
DOI: 10.1039/C8ME00049B

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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
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    [Original citation] - Published by The Royal Society of Chemistry.

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