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Issue 13, 2018
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From functional structure to packaging: full-printing fabrication of a microfluidic chip

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Abstract

This paper presents a concept of a full-printing methodology aiming at convenient and fast fabrication of microfluidic devices. For the first time, we achieved a microfluidic biochemical sensor with all functional structures fabricated by inkjet printing, including electrodes, immobilized enzymes, microfluidic components and packaging. With the cost-effective and rapid process, this method provides the possibility of quick model validation of a novel lab-on-chip system. In this study, a three-electrode electrochemical system was integrated successfully with glucose oxidase immobilization gel and sealed in an ice channel, forming a disposable microfluidic sensor for glucose detection. This fully-printed chip was characterized and showed good sensitivity and a linear section at a low-level concentration of glucose (0–10 mM). With the aid of automatic equipment, the fully-printed sensor can be massively produced with low cost.

Graphical abstract: From functional structure to packaging: full-printing fabrication of a microfluidic chip

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Publication details

The article was received on 30 Mar 2018, accepted on 18 May 2018 and first published on 23 May 2018


Article type: Paper
DOI: 10.1039/C8LC00327K
Citation: Lab Chip, 2018,18, 1859-1866
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    From functional structure to packaging: full-printing fabrication of a microfluidic chip

    F. Zheng, Z. Pu, E. He, J. Huang, B. Yu, D. Li and Z. Li, Lab Chip, 2018, 18, 1859
    DOI: 10.1039/C8LC00327K

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