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Issue 5, 2018
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Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial

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Abstract

Gut microbiota dysbiosis alters the intestinal barrier function, increases plasma lipopolysaccharide (LPS) levels, which promotes endotoxemia, and contributes to the onset and development of colorectal cancer (CRC). We report here for the first time the reduction of plasma LPS-binding protein (LBP) levels, a marker of endotoxemia, after pomegranate consumption in newly diagnosed CRC patients.

Graphical abstract: Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial

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Article information


Submitted
07 Feb 2018
Accepted
07 May 2018
First published
09 May 2018

Food Funct., 2018,9, 2617-2622
Article type
Communication

Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial

A. González-Sarrías, M. A. Núñez-Sánchez, M. A. Ávila-Gálvez, T. Monedero-Saiz, F. J. Rodríguez-Gil, F. Martínez-Díaz, M. V. Selma and J. C. Espín, Food Funct., 2018, 9, 2617
DOI: 10.1039/C8FO00264A

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