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Issue 5, 2018
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Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial

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Abstract

Gut microbiota dysbiosis alters the intestinal barrier function, increases plasma lipopolysaccharide (LPS) levels, which promotes endotoxemia, and contributes to the onset and development of colorectal cancer (CRC). We report here for the first time the reduction of plasma LPS-binding protein (LBP) levels, a marker of endotoxemia, after pomegranate consumption in newly diagnosed CRC patients.

Graphical abstract: Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial

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Publication details

The article was received on 07 Feb 2018, accepted on 07 May 2018 and first published on 09 May 2018


Article type: Communication
DOI: 10.1039/C8FO00264A
Food Funct., 2018,9, 2617-2622

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    Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia, in patients with newly diagnosed colorectal cancer: a randomized controlled clinical trial

    A. González-Sarrías, M. A. Núñez-Sánchez, M. A. Ávila-Gálvez, T. Monedero-Saiz, F. J. Rodríguez-Gil, F. Martínez-Díaz, M. V. Selma and J. C. Espín, Food Funct., 2018, 9, 2617
    DOI: 10.1039/C8FO00264A

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