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Issue 21, 2018
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Recent advances in chemical dearomatization of nonactivated arenes

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Abstract

Dearomatization reactions provide a synthetic connection between readily available, simple aromatic starting materials and more saturated intermediates of greater molecular complexity and synthetic utility. The last decade has witnessed a steady increase in the development of dearomative methods, providing new synthetic approaches to high-value building blocks and natural products. This review highlights advances both in the area of dearomatization methodologies for the most chemically inert arenes and in synthetic applications of such strategies.

Graphical abstract: Recent advances in chemical dearomatization of nonactivated arenes

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Publication details

The article was received on 10 May 2018 and first published on 03 Aug 2018


Article type: Review Article
DOI: 10.1039/C8CS00389K
Citation: Chem. Soc. Rev., 2018,47, 7996-8017
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    Recent advances in chemical dearomatization of nonactivated arenes

    W. C. Wertjes, E. H. Southgate and D. Sarlah, Chem. Soc. Rev., 2018, 47, 7996
    DOI: 10.1039/C8CS00389K

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