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Issue 10, 2018
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Multicomponent peptide assemblies

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Self-assembled peptide nanostructures have been increasingly exploited as functional materials for applications in biomedicine and energy. The emergent properties of these nanomaterials determine the applications for which they can be exploited. It has recently been appreciated that nanomaterials composed of multicomponent coassembled peptides often display unique emergent properties that have the potential to dramatically expand the functional utility of peptide-based materials. This review presents recent efforts in the development of multicomponent peptide assemblies. The discussion includes multicomponent assemblies derived from short low molecular weight peptides, peptide amphiphiles, coiled coil peptides, collagen, and β-sheet peptides. The design, structure, emergent properties, and applications for these multicomponent assemblies are presented in order to illustrate the potential of these formulations as sophisticated next-generation bio-inspired materials.

Graphical abstract: Multicomponent peptide assemblies

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Publication details

The article was received on 07 Feb 2018 and first published on 26 Apr 2018

Article type: Review Article
DOI: 10.1039/C8CS00115D
Citation: Chem. Soc. Rev., 2018,47, 3659-3720
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    Multicomponent peptide assemblies

    D. M. Raymond and B. L. Nilsson, Chem. Soc. Rev., 2018, 47, 3659
    DOI: 10.1039/C8CS00115D

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