Jump to main content
Jump to site search

Issue 13, 2018
Previous Article Next Article

Ligand libraries for high throughput screening of homogeneous catalysts

Author affiliations

Abstract

To accelerate the discovery of new or improved homogeneous catalysts, research groups in industry and academia have embraced high throughput experimentation (HTE). Such methodologies consist of preparing and testing large numbers of catalysts in parallel. Homogeneous metal catalysts are very well-suited for HTE, since in many cases, they can be prepared by simply mixing a metal precursor and a ligand. However, an HTE program requires a large set of chemically diverse ligands, i.e. a ligand library. In this review, we describe five different approaches for assembling ligand libraries based on an extensive survey of the literature. These approaches are based on commercial ligands, modular ligands, mixtures of ligands, supramolecular ligands or ligands prepared via the tools of biochemistry.

Graphical abstract: Ligand libraries for high throughput screening of homogeneous catalysts

Back to tab navigation

Publication details

The article was received on 26 Nov 2017 and first published on 08 May 2018


Article type: Review Article
DOI: 10.1039/C7CS00844A
Citation: Chem. Soc. Rev., 2018,47, 5038-5060
  •   Request permissions

    Ligand libraries for high throughput screening of homogeneous catalysts

    M. Renom-Carrasco and L. Lefort, Chem. Soc. Rev., 2018, 47, 5038
    DOI: 10.1039/C7CS00844A

Search articles by author

Spotlight

Advertisements