Issue 3, 2018

Cocrystal structure design for CH5134731 based on isomorphism

Abstract

We succeeded in forming a benzoic acid cocrystal of CH5134731 by focusing on the isomorphism shown by its solvates. As a result of evaluation, the benzoic acid cocrystal showed good solubility. This crystal engineering approach made it possible to reduce the amount of compound and study time in the early stage of research and development.

Graphical abstract: Cocrystal structure design for CH5134731 based on isomorphism

Supplementary files

Article information

Article type
Paper
Submitted
30 Oct 2017
Accepted
09 Dec 2017
First published
11 Dec 2017

CrystEngComm, 2018,20, 362-369

Cocrystal structure design for CH5134731 based on isomorphism

S. Tanida, N. Takata, R. Takano, A. Sakon, T. Ueto, K. Shiraki, K. Kadota, Y. Tozuka and M. Ishigai, CrystEngComm, 2018, 20, 362 DOI: 10.1039/C7CE01878A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements