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Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

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Abstract

We report a novel biomimetic drug discovery platform using high expression epidermal growth factor receptor (EGFR) HEK 293 cell membrane camouflaged magnetic nanoparticles. The EGFR/magnetic cell membrane nanoparticles (MCMNs) integrated desirable magnetic features and special binding bioaffinity. Application of this drug-targeting concept is expected to pave ways to a new drug discovery strategy.

Graphical abstract: Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

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Publication details

The article was received on 25 Oct 2018, accepted on 06 Nov 2018 and first published on 06 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08530G
Citation: Chem. Commun., 2018, Advance Article
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    Cell membrane camouflaged magnetic nanoparticles as a biomimetic drug discovery platform

    Y. Bu, Q. Hu, R. Ke, Y. Sui, X. Xie and S. Wang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC08530G

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