Jump to main content
Jump to site search


Assembly of glycoaminoacid building blocks: A new strategy for the straightforward synthesis of heparan sulfate mimics

Abstract

A new strategy that enables a modular straightforward synthesis of heparan sulfate oligosaccharide mimics by the assembly of simple glycoaminoacid building blocks is described. The coupling between units is readily carried out by an amidation reaction. Several glycoamino acid oligomers were prepared and their interaction with the FGF2 protein was analyzed.

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Oct 2018, accepted on 08 Nov 2018 and first published on 08 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08067D
Citation: Chem. Commun., 2018, Accepted Manuscript
  •   Request permissions

    Assembly of glycoaminoacid building blocks: A new strategy for the straightforward synthesis of heparan sulfate mimics

    A. Fernández-Mayoralas, J. Revuelta, R. Fuentes, L. Lagartera, M. J. HERNAIZ, A. Bastida and E. García-Junceda, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC08067D

Search articles by author

Spotlight

Advertisements