Jump to main content
Jump to site search

Issue 90, 2018
Previous Article Next Article

An oxaliplatin(IV) prodrug-based supramolecular self-delivery nanocarrier for targeted colorectal cancer treatment

Author affiliations

Abstract

A redox-responsive supramolecular nanocarrier was constructed from the self-assembly of spermine modified cyclodextrin and oxaliplatin prodrug. The nanocarrier could preferentially accumulate in polyamine transporter over-expressing HCT116 cells, releasing drugs under a reducing intracellular environment to maximize anticancer treatment.

Graphical abstract: An oxaliplatin(iv) prodrug-based supramolecular self-delivery nanocarrier for targeted colorectal cancer treatment

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Oct 2018, accepted on 18 Oct 2018 and first published on 19 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC07858K
Citation: Chem. Commun., 2018,54, 12762-12765
  •   Request permissions

    An oxaliplatin(IV) prodrug-based supramolecular self-delivery nanocarrier for targeted colorectal cancer treatment

    W. Q. Lim, S. Z. F. Phua, H. Chen and Y. Zhao, Chem. Commun., 2018, 54, 12762
    DOI: 10.1039/C8CC07858K

Search articles by author

Spotlight

Advertisements