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Mechanochemical carbon–carbon bond formation that proceeds via a cocrystal intermediate

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Abstract

We report the first cocrystal as an intermediate in a solid-state organic reaction wherein molecules of barbituric acid and vanillin assume a favorable orientation for the subsequent Knoevenagel condensation.

Graphical abstract: Mechanochemical carbon–carbon bond formation that proceeds via a cocrystal intermediate

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Publication details

The article was received on 01 Oct 2018, accepted on 31 Oct 2018 and first published on 31 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC07853J
Citation: Chem. Commun., 2018, Advance Article
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    Mechanochemical carbon–carbon bond formation that proceeds via a cocrystal intermediate

    S. Lukin, M. Tireli, I. Lončarić, D. Barišić, P. Šket, D. Vrsaljko, M. di Michiel, J. Plavec, K. Užarević and I. Halasz, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC07853J

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