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Issue 6, 2019
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Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

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Abstract

A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kgāˆ’1).

Graphical abstract: Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

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Publication details

The article was received on 28 Sep 2018, accepted on 07 Dec 2018 and first published on 08 Dec 2018


Article type: Communication
DOI: 10.1039/C8CC07768A
Chem. Commun., 2019,55, 790-793

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    Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

    C. Wu, X. Huang, Y. Tang, W. Xiao, L. Sun, J. Shao and X. Dong, Chem. Commun., 2019, 55, 790
    DOI: 10.1039/C8CC07768A

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