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Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

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Abstract

Pentose aminooxazolines and oxazolidinone thiones are considered as the key precursors which could have enabled the formation of RNA nucleotides under the conditions of early Earth. UV-irradiation experiments and quantum-chemical calculations demonstrate that these compounds are remarkably photostable and could accumulate over long periods of time in UV-rich prebiotic environments to undergo stereoisomeric purification.

Graphical abstract: Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

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Publication details

The article was received on 10 Sep 2018, accepted on 05 Nov 2018 and first published on 09 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC07343K
Citation: Chem. Commun., 2018, Advance Article
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    Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

    M. J. Janicki, S. J. Roberts, J. Šponer, M. W. Powner, R. W. Góra and R. Szabla, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC07343K

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