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Lighting up alkaline phosphatase in drug-induced liver injury using a new chemiluminescence resonance energy transfer nanoprobe

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Abstract

We present a new nanoprobe based on chemiluminescence resonance energy transfer for in vivo imaging of drug-induced alkaline phosphatase (ALP). This probe exhibits the perfect degrees of high sensitivity and specificity for real-time monitoring of ALP levels to directly evaluate drug-induced liver injury.

Graphical abstract: Lighting up alkaline phosphatase in drug-induced liver injury using a new chemiluminescence resonance energy transfer nanoprobe

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Publication details

The article was received on 05 Sep 2018, accepted on 05 Oct 2018 and first published on 11 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC07211F
Citation: Chem. Commun., 2018, Advance Article
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    Lighting up alkaline phosphatase in drug-induced liver injury using a new chemiluminescence resonance energy transfer nanoprobe

    X. Liu, N. Fan, L. Wu, C. Wu, Y. Zhou, P. Li and B. Tang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC07211F

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