Jump to main content
Jump to site search


One-step construction of molecular complexity by tert-butyl nitrite (TBN)-initiated cascade α,β-sp3 C–H bond difunctionalization and C–N bond cleavage

Author affiliations

Abstract

TBN-initiated cascade multifunctionalization of inert C–H and C–N bonds in N-arylazacycles has been realized under transition-metal free conditions, in which the synthetically useful oxime, N–NO and aldehyde functional groups were constructed in only one synthetic step.

Graphical abstract: One-step construction of molecular complexity by tert-butyl nitrite (TBN)-initiated cascade α,β-sp3 C–H bond difunctionalization and C–N bond cleavage

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Sep 2018, accepted on 25 Oct 2018 and first published on 26 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC06946H
Citation: Chem. Commun., 2018, Advance Article
  •   Request permissions

    One-step construction of molecular complexity by tert-butyl nitrite (TBN)-initiated cascade α,β-sp3 C–H bond difunctionalization and C–N bond cleavage

    K. He, P. Li, S. Zhang, Q. Chen, H. Ji, Y. Yuan and X. Jia, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC06946H

Search articles by author

Spotlight

Advertisements