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Issue 82, 2018
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DNA-Mediated rolling circle amplification for ultrasensitive detection of thrombin using MALDI-TOF mass spectrometry

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Abstract

A DNA-mediated rolling circle amplification (RCA) strategy was established for ultrasensitive and specific detection of thrombin via matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). This platform provides a versatile assay for the detection of various biomolecules of low abundance.

Graphical abstract: DNA-Mediated rolling circle amplification for ultrasensitive detection of thrombin using MALDI-TOF mass spectrometry

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Publication details

The article was received on 26 Aug 2018, accepted on 21 Sep 2018 and first published on 21 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC06934D
Citation: Chem. Commun., 2018,54, 11546-11549
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    DNA-Mediated rolling circle amplification for ultrasensitive detection of thrombin using MALDI-TOF mass spectrometry

    Z. Wu, L. Lin, M. Khan, W. Zhang, S. Mao, Y. Zheng, Z. Li and J. Lin, Chem. Commun., 2018, 54, 11546
    DOI: 10.1039/C8CC06934D

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