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A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis

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Abstract

A graphene-based nanocarrier modified with death receptor 4 (DR4) antibody and AKT siRNA has been developed, which can synergistically strengthen death receptor-mediated apoptosis and enhance the cancer therapeutic effect in vivo.

Graphical abstract: A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis

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Publication details

The article was received on 21 Aug 2018, accepted on 06 Nov 2018 and first published on 06 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC06796A
Citation: Chem. Commun., 2018, Advance Article
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    A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis

    W. Pan, S. Gong, Y. Li, H. Zhang, N. Li and B. Tang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC06796A

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