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Issue 87, 2018
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p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

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Abstract

A p-toluenesulfonic acid catalyzed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centers has been developed, featuring a broad substrate scope, environmentally benign reaction conditions, and operational simplicity.

Graphical abstract: p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

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Publication details

The article was received on 15 Aug 2018, accepted on 09 Oct 2018 and first published on 09 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC06643D
Citation: Chem. Commun., 2018,54, 12377-12380

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    p-Toluenesulfonic acid catalysed fluorination of α-branched ketones for the construction of fluorinated quaternary carbon centres

    S. Tang, H. Bian, Z. Zhan, M. Chen, J. Lv, S. Xie and F. Zhang, Chem. Commun., 2018, 54, 12377
    DOI: 10.1039/C8CC06643D

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