Issue 65, 2018
From the journal:

Chemical Communications

Real-time tracing the changes in the intracellular pH value during apoptosis by near-infrared ratiometric fluorescence imaging†

Liyun Lin, ORCID logo a   Jingjin Zhao, ORCID logo *a   Liangliang Zhang, ORCID logo a   Yong Huang,a   Fanggui Ye ORCID logo a  and  Shulin Zhao ORCID logo *a  

* Corresponding authors

a State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, China
E-mail: jzhao12@163.com, zhaoshulin001@163.com

Abstract

We developed a near-infrared ratiometric fluorescent nanoprobe with single-excitation dual-emission. The proposed nanoprobe was applied for real-time monitoring the changes in the pH value during hydrogen peroxide-induced apoptosis by ratio imaging. The pH value of HeLa cells changed from 6.6 to 5.6 after H2O2 (100 μM) stimulation for 40 min.

Graphical abstract: Real-time tracing the changes in the intracellular pH value during apoptosis by near-infrared ratiometric fluorescence imaging

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8CC05385E
Article type
Communication
Submitted
04 Jul 2018
Accepted
23 Jul 2018
First published
23 Jul 2018

Chem. Commun., 2018,54, 9071-9074

Permissions

Request permissions

Real-time tracing the changes in the intracellular pH value during apoptosis by near-infrared ratiometric fluorescence imaging

L. Lin, J. Zhao, L. Zhang, Y. Huang, F. Ye and S. Zhao, Chem. Commun., 2018, 54, 9071 DOI: 10.1039/C8CC05385E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements