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Issue 72, 2018
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An active DNA-based nanoprobe for photoacoustic pH imaging

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Abstract

We report an active DNA construct capable of probing pH through a photoacoustic (PA) ratiometric analysis approach. Our nanoprobe enables different PA readout in tissue mimicking phantoms in the range between pH 6.8 to 7.8 at physiologically relevant sodium concentrations. Thus, it represents a promising platform to probe pH values relevant to the tumor microenvironment using PA.

Graphical abstract: An active DNA-based nanoprobe for photoacoustic pH imaging

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Publication details

The article was received on 19 May 2018, accepted on 11 Jul 2018 and first published on 23 Aug 2018


Article type: Communication
DOI: 10.1039/C8CC04007A
Citation: Chem. Commun., 2018,54, 10176-10178
  • Open access: Creative Commons BY license
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    An active DNA-based nanoprobe for photoacoustic pH imaging

    K. N. Baumann, A. C. Fux, J. Joseph, S. E. Bohndiek and S. Hernández-Ainsa, Chem. Commun., 2018, 54, 10176
    DOI: 10.1039/C8CC04007A

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