Jump to main content
Jump to site search

Issue 52, 2018
Previous Article Next Article

Rapid synthesis of polysubstituted phenanthridines from simple aliphatic/aromatic nitriles and iodo arenes via Pd(II) catalyzed domino C–C/C–C/C–N bond formation

Author affiliations

Abstract

An efficient and straightforward method has been developed for the synthesis of polysubstituted phenanthridines from simple aryl iodides and alkyl/aryl nitriles via the palladium-catalyzed nucleophilic addition of aryl iodides to nitriles followed by cascade formation of C–C and C–N bonds viz. in situ generated imine directed sequential two fold C–H activation.

Graphical abstract: Rapid synthesis of polysubstituted phenanthridines from simple aliphatic/aromatic nitriles and iodo arenes via Pd(ii) catalyzed domino C–C/C–C/C–N bond formation

Back to tab navigation

Supplementary files

Publication details

The article was received on 03 May 2018, accepted on 01 Jun 2018 and first published on 05 Jun 2018


Article type: Communication
DOI: 10.1039/C8CC03556C
Citation: Chem. Commun., 2018,54, 7207-7210
  •   Request permissions

    Rapid synthesis of polysubstituted phenanthridines from simple aliphatic/aromatic nitriles and iodo arenes via Pd(II) catalyzed domino C–C/C–C/C–N bond formation

    Y. Jaiswal, Y. Kumar, J. Pal, R. Subramanian and A. Kumar, Chem. Commun., 2018, 54, 7207
    DOI: 10.1039/C8CC03556C

Search articles by author

Spotlight

Advertisements