Platinum(IV) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

Qiling Chen; Yuanyuan Yang; Xun Lin; Wen Ma; Gui Chen; Wenliang Li; Xuefeng Wang; Zhiqiang Yu

doi:10.1039/C8CC02791A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Platinum(iv) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance†

Qiling Chen,‡^a Yuanyuan Yang,‡^a Xun Lin,^a Wen Ma,^a Gui Chen,^a Wenliang Li,^b Xuefeng Wang*^c and Zhiqiang Yu

*^a

Author affiliations

* Corresponding authors

^a Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China
E-mail: yuzq@smu.edu.cn

^b School of Pharmacy, Jilin Medical University, Jilin 132013, China

^c Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China
E-mail: 15913130306@163.com

Abstract

Platinum(IV) prodrugs of clinically used cisplatin and oxaliplatin with two axial long lipid chains were developed for nanoparticle delivery to combat cisplatin resistance.

Download options Please wait...

Supplementary files

Supplementary information PDF (630K)

Article information

DOI: https://doi.org/10.1039/C8CC02791A
Article type: Communication
Submitted: 09 Apr 2018
Accepted: 30 Apr 2018
First published: 01 May 2018

Download Citation

Chem. Commun., 2018,54, 5369-5372

Permissions

Request permissions

Platinum(IV) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

Q. Chen, Y. Yang, X. Lin, W. Ma, G. Chen, W. Li, X. Wang and Z. Yu, Chem. Commun., 2018, 54, 5369 DOI: 10.1039/C8CC02791A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Platinum(iv) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Platinum(IV) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

Social activity

Search articles by author

Spotlight

Advertisements