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Issue 53, 2018
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Nonconventional regeneration of redox enzymes – a practical approach for organic synthesis?

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Abstract

Oxidoreductases have become useful tools in the hands of chemists to perform selective and mild oxidation and reduction reactions. Instead of mimicking native catalytic cycles, generally involving costly and unstable nicotinamide cofactors, more direct, NAD(P)-independent methodologies are being developed. The promise of these approaches not only lies with simpler and cheaper reaction schemes but also with higher selectivity as compared to whole cell approaches and their mimics.

Graphical abstract: Nonconventional regeneration of redox enzymes – a practical approach for organic synthesis?

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Publication details

The article was received on 20 Mar 2018, accepted on 19 Apr 2018 and first published on 20 Apr 2018


Article type: Feature Article
DOI: 10.1039/C8CC02219D
Chem. Commun., 2018,54, 7281-7289

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    Nonconventional regeneration of redox enzymes – a practical approach for organic synthesis?

    W. Zhang and F. Hollmann, Chem. Commun., 2018, 54, 7281
    DOI: 10.1039/C8CC02219D

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