Jump to main content
Jump to site search

Issue 32, 2018
Previous Article Next Article

A missing member of conjugated N-heterocycles: realizing pyrido[1,2-α]azepine by reacting ruthenium alkenylcarbene complex with alkyne

Author affiliations

Abstract

Despite the excellent chemical properties of N-heterocycles, pyrido[1,2-α]azepine remains elusive due to its potential antiaromaticity and lability. Herein, we demonstrate the synthesis and characterization of the first bicyclic pyrido[1,2-α]azepine that leverages the coordination to the ruthenium center to promote the stability of N-bridged bicycle.

Graphical abstract: A missing member of conjugated N-heterocycles: realizing pyrido[1,2-α]azepine by reacting ruthenium alkenylcarbene complex with alkyne

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 Jan 2018, accepted on 20 Mar 2018 and first published on 21 Mar 2018


Article type: Communication
DOI: 10.1039/C8CC00758F
Chem. Commun., 2018,54, 4009-4012

  •   Request permissions

    A missing member of conjugated N-heterocycles: realizing pyrido[1,2-α]azepine by reacting ruthenium alkenylcarbene complex with alkyne

    X. Zhou, F. Huang, C. Tang, Q. Zhuo, Z. Chen, H. Zhang and H. Xia, Chem. Commun., 2018, 54, 4009
    DOI: 10.1039/C8CC00758F

Search articles by author

Spotlight

Advertisements