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Issue 14, 2018
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An allylated firefly luciferin analogue with luciferase specific response in living cells

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Abstract

An allylated firefly luciferin was successfully synthesized and its bioluminescence properties were evaluated. When applied to cellular imaging in combination with Eluc, which is one of the commercially available luciferases, this analogue displayed a luciferase-specific bioluminescence signal with prolonged emission (>100 min).

Graphical abstract: An allylated firefly luciferin analogue with luciferase specific response in living cells

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Publication details

The article was received on 20 Dec 2017, accepted on 19 Jan 2018 and first published on 24 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC09720D
Citation: Chem. Commun., 2018,54, 1774-1777

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    An allylated firefly luciferin analogue with luciferase specific response in living cells

    Y. Ikeda, T. Saitoh, K. Niwa, T. Nakajima, N. Kitada, S. A. Maki, M. Sato, D. Citterio, S. Nishiyama and K. Suzuki, Chem. Commun., 2018, 54, 1774
    DOI: 10.1039/C7CC09720D

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