Issue 7, 2018
From the journal:

Chemical Communications

Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism†

Jiaheng Sun,ab   Qi Xin,b   Yang Yang, ORCID logo *b   Hameed Shah,b   Hongqian Cao,ab   Yanfei Qi,*a   Jian Ru Gong*b  and  Junbai Li ORCID logo c  

* Corresponding authors

a School of Public Health, Jilin University, Changchun, China
E-mail: qiyanfei@jlu.edu.cn

b CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China
E-mail: yangyang@nanoctr.cn, gongjr@nanoctr.cn

c CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China

Abstract

A novel material with a large two-photon absorption cross-section was conjugated with a typical photosensitizer for inducing a FRET process. The photosensitizer can be excited by a one-/two-photon laser and then induced photo-toxicity in vitro and in vivo. The system presents great potential for improving treatment depth and the precision of traditional photodynamic therapy.

Graphical abstract: Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C7CC08820E
Article type
Communication
Submitted
16 Nov 2017
Accepted
29 Nov 2017
First published
29 Nov 2017

Chem. Commun., 2018,54, 715-718

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Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism

J. Sun, Q. Xin, Y. Yang, H. Shah, H. Cao, Y. Qi, J. R. Gong and J. Li, Chem. Commun., 2018, 54, 715 DOI: 10.1039/C7CC08820E

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