Aldehyde-functionalized metal–organic frameworks for selective sensing of homocysteine over Cys, GSH and other natural amino acids†
Abstract
A novel aldehyde-functionalized porous metal–organic framework (MOF) material has been constructed that can act as the first example of MOF-implicated sensors for discriminating Hcy from natural amino acids and even thiol-related peptides (GSH) with high sensitivity (LOD = 40 nM). The sensing mechanism is also discussed.