Issue 11, 2018

Self-healing, stretchable and robust interpenetrating network hydrogels


A self-healable stretchable hydrogel system that can be readily synthesized while also possessing robust compressive strength has immense potential for regenerative medicine. Herein, we have explored the addition of commercially available unfunctionalized polysaccharides as a route to synthesize self-healing, stretchable poly(ethylene glycol) (PEG) interpenetrating networks (IPNs) as extracellular matrix (ECM) mimics. The introduction of self-healing and stretchable properties has been achieved while maintaining the robust mechanical strength of the orginal, single network PEG-only hydrogels (ultimate compressive stress up to 2.4 MPa). This has been accomplished without the need for complicated and expensive functionalization of the natural polymers, enhancing the translational applicability of these new biomaterials.

Graphical abstract: Self-healing, stretchable and robust interpenetrating network hydrogels

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Article information

Article type
25 Jul 2018
09 Sep 2018
First published
10 Sep 2018
This article is Open Access
Creative Commons BY license

Biomater. Sci., 2018,6, 2932-2937

Self-healing, stretchable and robust interpenetrating network hydrogels

L. J. Macdougall, M. M. Pérez-Madrigal, J. E. Shaw, M. Inam, J. A. Hoyland, R. O'Reilly, S. M. Richardson and A. P. Dove, Biomater. Sci., 2018, 6, 2932 DOI: 10.1039/C8BM00872H

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