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Issue 24, 2018
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Biomedical applications of mid-infrared quantum cascade lasers – a review

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Abstract

Mid-infrared spectroscopy has been applied to research in biology and medicine for more than 20 years and conceivable applications have been identified. More recently, these applications have been shown to benefit from the use of quantum cascade lasers due to their specific properties, namely high spectral power density, small beam parameter product, narrow emission spectrum and, if needed, tuning capabilities. This review provides an overview of the achievements and illustrates some applications which benefit from the key characteristics of quantum cascade laser-based mid-infrared spectroscopy using examples such as breath analysis, the investigation of serum, non-invasive glucose monitoring in bulk tissue and the combination of spectroscopy and microscopy of tissue thin sections for rapid histopathology.

Graphical abstract: Biomedical applications of mid-infrared quantum cascade lasers – a review

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Publication details

The article was received on 15 Jul 2018, accepted on 02 Oct 2018 and first published on 24 Oct 2018


Article type: Critical Review
DOI: 10.1039/C8AN01306C
Citation: Analyst, 2018,143, 5888-5911
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    Biomedical applications of mid-infrared quantum cascade lasers – a review

    K. Isensee, N. Kröger-Lui and W. Petrich, Analyst, 2018, 143, 5888
    DOI: 10.1039/C8AN01306C

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