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Issue 15, 2017
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A long-lived iridium(iii) chemosensor for the real-time detection of GHB

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Gamma-hydroxybutyric acid (GHB) is a commonly used “date rape” drug in drug-facilitated sexual assaults (DFSA) due to its low price and ready availability, and it is more quickly excreted from the human body than other drugs. Therefore, the development of a real-time detection method for GHB could help facilitate law enforcement agencies in tackling DFSA. In this work, a long-lived iridium(III) chemosensor 1 has been synthesized for the switch-off detection of GHB. Upon addition of GHB to an aqueous solution of the iridium(III) complex 1, a significant luminescence quenching occurred that could be observed by the naked eye under UV illumination. The luminescence signal of the iridium(III) complex 1 could also be distinguished from strongly fluorescent media using time-resolved emission spectroscopy.

Graphical abstract: A long-lived iridium(iii) chemosensor for the real-time detection of GHB

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The article was received on 31 Dec 2016, accepted on 20 Mar 2017 and first published on 21 Mar 2017

Article type: Communication
DOI: 10.1039/C6TB03396B
J. Mater. Chem. B, 2017,5, 2739-2742

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    A long-lived iridium(III) chemosensor for the real-time detection of GHB

    W. Wang, Z. Dong, G. Yang, C. Leung, S. Lin and D. Ma, J. Mater. Chem. B, 2017, 5, 2739
    DOI: 10.1039/C6TB03396B

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