Jump to main content
Jump to site search

Issue 79, 2017, Issue in Progress
Previous Article Next Article

Self-emulsification of eugenol by modified rice proteins to design nano delivery systems for controlled release of caffeic acid phenethyl ester

Author affiliations

Abstract

The self-emulsification of oils containing dissolved solutes is not only an intriguing phenomenon but is also of practical interest in the delivery of agricultural chemicals and drugs. Herein, a facile one-step self-emulsification of eugenol with tunable release rates of encapsulated lipophilic compounds was enabled simply by gently mixing eugenol with modified rice proteins (MRPs). Due to binding with eugenol by hydrophobic interactions lowering the oil/water interfacial tension, MRPs underwent secondary structure changes and precipitated on eugenol droplets of nanoscale. Increasing the MRP : eugenol ratio enabled the formation of more porous interfacial films to increase the first-order release rate of eugenol and the resultant anti-proliferation activity of encapsulated caffeic acid phenethyl ester (CAPE) against HTC-116 human colorectal cancer cells. Therefore, novel emulsions with varied interfacial structures can be fabricated utilizing MRPs to control release characteristics and bioactivity of lipophilic compounds.

Graphical abstract: Self-emulsification of eugenol by modified rice proteins to design nano delivery systems for controlled release of caffeic acid phenethyl ester

Back to tab navigation

Publication details

The article was received on 01 Sep 2017, accepted on 13 Oct 2017 and first published on 26 Oct 2017


Article type: Paper
DOI: 10.1039/C7RA09712C
RSC Adv., 2017,7, 49953-49961
  • Open access: Creative Commons BY license
  •   Request permissions

    Self-emulsification of eugenol by modified rice proteins to design nano delivery systems for controlled release of caffeic acid phenethyl ester

    T. Wang, H. Chen, R. Wang, Z. Chen and Q. Zhong, RSC Adv., 2017, 7, 49953
    DOI: 10.1039/C7RA09712C

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements