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Issue 52, 2017, Issue in Progress
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Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

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Abstract

Thiazolines and thiazoles are an integral part of numerous natural products, a number of drugs, and many useful molecules such as ligands for metal catalysis. We report the first common synthetic protocol for the synthesis of thiazoles and thiazolines. Novel molecules are efficiently synthesized by using readily available and inexpensive substrates. The reaction conditions are mild and pure products are obtained without work-up and column purification.

Graphical abstract: Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

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Article information


Submitted
29 May 2017
Accepted
21 Jun 2017
First published
26 Jun 2017

This article is Open Access

RSC Adv., 2017,7, 32647-32651
Article type
Paper

Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

Z. A. Alsharif and M. A. Alam, RSC Adv., 2017, 7, 32647
DOI: 10.1039/C7RA05993K

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    [Original citation] - Published by The Royal Society of Chemistry.

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