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Issue 29, 2017, Issue in Progress
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Preparation of [18F]-NHC-BF3 conjugates and their applications in PET imaging

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Abstract

N-Heterocyclic carbene boron trifluoride (NHC-BF3) conjugates were successfully radiofluorinated by SnCl4-promoted 18F–19F isotopic exchange reaction in one labelling step. This method afforded in vivo stable PET agents that efficiently bound to targeted tumours yielding PET images with good tumour-to-background contrast.

Graphical abstract: Preparation of [18F]-NHC-BF3 conjugates and their applications in PET imaging

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Publication details

The article was received on 29 Dec 2016, accepted on 14 Mar 2017 and first published on 22 Mar 2017


Article type: Paper
DOI: 10.1039/C6RA28806E
RSC Adv., 2017,7, 17748-17751
  • Open access: Creative Commons BY-NC license
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    Preparation of [18F]-NHC-BF3 conjugates and their applications in PET imaging

    K. Chansaenpak, M. Wang, H. Wang, B. C. Giglio, F. P. Gabbaï, Z. Wu and Z. Li, RSC Adv., 2017, 7, 17748
    DOI: 10.1039/C6RA28806E

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