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Issue 6, 2017, Issue in Progress
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Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(II) ions

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Abstract

Two simple fluorescent sensors for Cu(II) ions were synthesized in two reaction steps, using recently developed C–H functionalization reactions for boron dipyrrins, starting from a standard 8-aryl-BODIPY dye and a tris(2-aminoethyl)amine (TREN) ligand. At pH 5, the resulting BODIPY–TREN conjugates are demonstrated to be promising, highly selective, water soluble, Cu(II) sensors that can permeate the cell membrane.

Graphical abstract: Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(ii) ions

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Publication details

The article was received on 24 Nov 2016, accepted on 20 Dec 2016 and first published on 13 Jan 2017


Article type: Paper
DOI: 10.1039/C6RA27299A
Citation: RSC Adv., 2017,7, 3066-3071
  • Open access: Creative Commons BY license
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    Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(II) ions

    B. Verbelen, M. Valckenborgh, M. Inclán, A. Nebot, W. Dehaen and E. García-España, RSC Adv., 2017, 7, 3066
    DOI: 10.1039/C6RA27299A

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