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Issue 55, 2017, Issue in Progress
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Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties

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Abstract

Electrospun scaffolds of poly(glycerol sebacate)/poly(ε-caprolactone) (PGS/PCL) have been used for engineered tissues due to their desirable thermal and mechanical properties as well as their tunable degradability. In this paper, we fabricated micro-fibrous scaffolds from a composite of PGS/PCL using a standard electrospinning method and coated them with silver (Ag). The low temperature coating method prevented substrate melting and the Ag coating decreases the pore size and increases the diameter of fibers which resulted in enhanced thermal and mechanical properties. We further compared the mechanical properties of the composite fibrous scaffolds with different thicknesses of Ag coated scaffolds. The composite fibrous scaffold with a 275 nm Ag coating showed higher tensile modulus (E) and ultimate tensile strength (UTS) without any post-processing treatment. Lastly, potential controlled release of the Ag coating from the composite fibrous scaffolds could present interesting biomedical applications.

Graphical abstract: Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties

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Supplementary files

Article information


Submitted
12 Oct 2016
Accepted
14 Jun 2017
First published
07 Jul 2017

This article is Open Access

RSC Adv., 2017,7, 34331-34338
Article type
Paper

Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties

Parvathalu. Kalakonda, M. A. Aldhahri, M. S. Abdel-wahab, A. Tamayol, K. M. Moghaddam, F. Ben Rached, A. Pain, A. Khademhosseini, A. Memic and S. Chaieb, RSC Adv., 2017, 7, 34331
DOI: 10.1039/C6RA25151J

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