Issue 2, 2017

A colorimetric and fluorescent pH probe for imaging in E. coli cells

Abstract

A colorimetric and fluorescent pH probe 1-(4-methylphenyl)-3-(4-dimethylaminophenyl) acrylketone (MDAK) was facilely prepared. The probe exhibited strong pH-dependent behavior and responded linearly and rapidly to minor pH fluctuations within the range of 1.53–3.96. In addition, MDAK displayed a notably large Stokes shift of 121 nm. MDAK possessed a highly selective response to H+ over other metal ions, amion acids and displayed good photostability and excellent reversibility. Furthermore, it can be applied to visualize extreme acidity in E. coli cells.

Graphical abstract: A colorimetric and fluorescent pH probe for imaging in E. coli cells

Supplementary files

Article information

Article type
Paper
Submitted
08 Oct 2016
Accepted
06 Nov 2016
First published
04 Jan 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 964-970

A colorimetric and fluorescent pH probe for imaging in E. coli cells

J. Chao, K. Song, H. Wang, Z. Li, Y. Zhang, C. Yin, F. Huo, J. Wang and T. Zhang, RSC Adv., 2017, 7, 964 DOI: 10.1039/C6RA24885C

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