Synthesis of fully-substituted 1,2,3-triazoles via copper(i)-catalyzed three-component coupling of sulfoximines, alkynes and azides

Abstract

A copper(I)-catalyzed three-component reaction of sulfoximines, alkynes and azides is described. This reaction proceeds under mild conditions with copper salt as a catalyst and atmospheric oxygen as an oxidant to afford a variety of 1,2,3-triazolyl-5-sulfoximines in moderate to good yields.