Cycloadduct formation of α,β-unsaturated esters with azides catalyzed by NHC systems

Abstract

NHC-catalyzed cycloadduct formation of α,β-unsaturated esters with azides has been developed. This strategy could generate 1,2,3-triazoles and dihydropyrazoles with high yields and regioselectivities in the presence of an N-heterocyclic carbene catalyst. The broad substrate scope and mechanistic survey of this process are also presented.