Issue 30, 2017

19F CEST imaging probes for metal ion detection

Abstract

For detecting metal ions with 19F chemical exchange saturation transfer magnetic resonance imaging (19F CEST MRI), a class of novel fluorinated chelators with diverse fluorine contents and chelation properties were conveniently synthesized on gram scales. Among them, a DTPA-derived chelator with high sensitivity and selectivity was identified as a novel 19F CEST imaging probe for simultaneously detecting multiple metal ions.

Graphical abstract: 19F CEST imaging probes for metal ion detection

Supplementary files

Article information

Article type
Paper
Submitted
03 May 2017
Accepted
14 Jul 2017
First published
14 Jul 2017

Org. Biomol. Chem., 2017,15, 6441-6446

19F CEST imaging probes for metal ion detection

Q. Peng, Y. Yuan, H. Zhang, S. Bo, Y. Li, S. Chen, Z. Yang, X. Zhou and Z. Jiang, Org. Biomol. Chem., 2017, 15, 6441 DOI: 10.1039/C7OB01068K

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