A cascade C–H functionalization/cyclization reaction of N-arylpyridin-2-amines with α,β-unsaturated aldehydes for the synthesis of dihydroquinolinone derivatives under rhodium catalysis

Abstract

A novel cascade C–H functionalization/cyclization reaction of N-arylpyridin-2-amines with α,β-unsaturated aldehydes has been developed under rhodium catalysis, affording dihydroquinolinone derivatives in moderate to excellent yields. A plausible mechanism of dual catalytic cycles by rhodium(III) catalysis is also proposed.