Issue 16, 2017
From the journal:

Organic & Biomolecular Chemistry

Post-synthetic modification of tryptophan containing peptides via NIS mediation†

Chen-Xue Gu,‡a   Qing-Wei Bi,‡b   Chu-Kun Gao,a   Jian Wen,a   Zhi-Gang Zhao*b  and  Zili Chen ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Renmin University of China, Beijing 100872, China
E-mail: zilichen@ruc.edu.cn

b College of Chemistry & Environment Protection Engineering, Southwest University for Nationalities, Chengdu 610041, China
E-mail: zzg63129@yahoo.com.cn

Abstract

A new efficient method was developed to provide modified tryptophan peptides through NIS (N-iodosuccinimide) mediated N2-selective coupling of a Trp unit with 1,2,3-triazoles, of which, the preliminary spectral properties were also studied.

Graphical abstract: Post-synthetic modification of tryptophan containing peptides via NIS mediation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7OB00329C
Article type
Communication
Submitted
11 Feb 2017
Accepted
20 Mar 2017
First published
20 Mar 2017

Org. Biomol. Chem., 2017,15, 3396-3400

Permissions

Request permissions

Post-synthetic modification of tryptophan containing peptides via NIS mediation

C. Gu, Q. Bi, C. Gao, J. Wen, Z. Zhao and Z. Chen, Org. Biomol. Chem., 2017, 15, 3396 DOI: 10.1039/C7OB00329C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements