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Issue 3, 2017
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C–H functionalisation of cycloalkanes

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Abstract

Among organic compounds hydrocarbons are inexpensive and possibly the most abundant among natural resources. Developing strategies for selective functionalisation of inert hydrocarbon C–H bonds is one of the most ideal synthetic paths that a synthetic chemist could think of. This critical review focuses on the recent development of various directed and non-directed cycloalkylations leading to the formation of carbon–carbon (C–C) and carbon–heteroatom (C–X) bonds. Apart from various transition metal catalysed cycloalkylations, this review also covers various metal-free cycloalkylation processes.

Graphical abstract: C–H functionalisation of cycloalkanes

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Article information


Submitted
07 Sep 2016
Accepted
25 Nov 2016
First published
25 Nov 2016

Org. Biomol. Chem., 2017,15, 505-530
Article type
Review Article

C–H functionalisation of cycloalkanes

A. Banerjee, S. Sarkar and B. K. Patel, Org. Biomol. Chem., 2017, 15, 505
DOI: 10.1039/C6OB01975G

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