Issue 43, 2017
From the journal:

Nanoscale

Engineered phage nanofibers induce angiogenesis†

So Young Yoo, ORCID logo *ab   Kshitiz Raj Shrestha,a   Su-Nam Jeong,a   Jeong-In Kangb  and  Seung-Wuk Leec  

* Corresponding authors

a BIO-IT Foundry Technology Institute, Pusan National University, Busan 46241, Republic of Korea
E-mail: yoosy2@gmail.com, yoosy@pusan.ac.kr

b Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea

c Department of Bioengineering, University of California, Berkeley, CA 94720, USA
E-mail: leesw@berkeley.edu

Abstract

Herein, we exploited a bioinspired M13 bacteriophage as an angiogenic nanofiber for soft tissue engineering applications. We demonstrated that engineered phage nanofibers induce angiogenesis with specific biochemical and topological cues. Specifically, nanofibrous phage structures provided a novel therapeutic platform for stem cell technologies in ischemic diseases.

Graphical abstract: Engineered phage nanofibers induce angiogenesis

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Article information

DOI
https://doi.org/10.1039/C7NR03332J
Article type
Paper
Submitted
11 May 2017
Accepted
04 Oct 2017
First published
06 Oct 2017

Nanoscale, 2017,9, 17109-17117

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Engineered phage nanofibers induce angiogenesis

S. Y. Yoo, K. R. Shrestha, S. Jeong, J. Kang and S. Lee, Nanoscale, 2017, 9, 17109 DOI: 10.1039/C7NR03332J

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